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Research Investigates the Role of Genetics and Lifestyle in Alzheimer’s Risk

HudsonAlpha Launches Alzheimer’s Risk Study Integrating Genetics and Lifestyle

HUNTSVILLE, Ala. — The HudsonAlpha Institute for Biotechnology, in collaboration with the Smith Family Clinic for Genomic Medicine, has announced the launch of the "Hope AD" study, aimed at exploring how genetic and lifestyle factors influence the risk of developing Alzheimer’s disease.

The initiative intends to identify individuals at heightened risk for Alzheimer’s by analyzing genetic markers, blood biomarkers, and various lifestyle factors, including diet and exercise habits. "The idea is to understand the interplay between genetics and lifestyle when it comes to Alzheimer’s and other types of dementia," said Megan Cochran, director of the Smith Family Clinic.

Participants will undergo screening to select approximately 50 individuals identified as high-risk. These individuals will participate in a six-month lifestyle intervention program, which includes consultations with a dietitian and health coach, access to a brain training app, and progress tracking through fitness monitoring.

Cochran explained that while there is a substantial understanding of the genetic components associated with Alzheimer’s risk, including certain high-impact genes and others with milder effects, the cumulative risk factors from these genes are still being studied.

The Smith Family Clinic is actively recruiting 200 participants aged 65 to 75, particularly those with a close family member diagnosed with Alzheimer’s or dementia. Enrollment in the study offers a unique opportunity for individuals to contribute to vital research while possibly benefiting from targeted lifestyle interventions.

For more information about participation in the study, interested individuals can visit HudsonAlpha’s website or contact the clinic at 256-327-9640. This research represents an important step in understanding and potentially mitigating the risks associated with Alzheimer’s disease.

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